Venlafaxine

Venlafaxine is an antidepressant forming part of the class of drugs known as serotonin-noradrenaline reuptake inhibitors (SNRIs). SNRIs inhibit the reuptake of the neurotransmitters serotonin and noradrenaline in the brain. They are closely related to SSRIs, although the latter only inhibit the reuptake of serotonin. Venlafaxine is prescribed to treat depression, anxiety disorders, neuralgia and hot flushes during the menopause.

Venlafaxine and the benefit of DNA analysis

The rate at which venlafaxine is processed within your body varies from one individual to another. This means that the efficacy and side effects of venlafaxine can be predicted to some extent on the basis of your genes. Preventive DNA analysis can therefore be an important tool in optimising your medication.

Venlafaxine and the enzyme CYP2D6

Venlafaxine is processed within the body primarily by the enzyme CYP2D6. The activity of this enzyme can vary considerably depending on your genetic predisposition, which means the efficacy of venlafaxine can also differ from person to person.

Information about your genetic predisposition may therefore provide grounds for extra vigilance in relation to a treatment with venlafaxine.

Read more about The enzyme CYP2D6 »