Paroxetine

Paroxetine is an antidepressant forming part of the class of drugs known as selective serotonin reuptake inhibitors (SSRIs). It inhibits the reuptake of the neurotransmitter serotonin in the brain. Paroxetine improves the mood and reduces anxiety, and is used to treat depression, anxiety disorders, neuralgia, certain types of itch, premature ejaculation and hot flushes during the menopause.

Paroxetine and the benefit of DNA analysis

The rate at which paroxetine is processed within your body varies from one individual to another. This means that the efficacy and side effects of paroxetine can be predicted to some extent on the basis of your genes. Preventive DNA analysis can therefore be an important tool in optimising your medication.

Paroxetine and the enzyme CYP2D6

Paroxetine is processed within the body primarily by the enzyme CYP2D6. The activity of this enzyme can vary considerably depending on your genetic predisposition, which means the efficacy of paroxetine can also differ from person to person.

Information about your genetic predisposition may therefore provide grounds for extra vigilance in relation to a treatment with paroxetine.

Read more about The enzyme CYP2D6 »