Flecainide

Flecainide is an antiarrhythmic drug forming part of the class of drugs known as class 1C antiarrhythmics (sodium channel blockers). Flecainide decreases and regulates the heart rate by slowing the conduction of impulses through the nerves and decreasing the sensitivity of the heart muscle. It is prescribed to treat cardiac arrhythmia (such as atrial fibrillation) as well as to prevent arrhythmias.

Flecainide and the benefit of DNA analysis

The rate at which flecainide is processed within your body varies from one individual to another. This means that the efficacy and side effects of flecainide can be predicted to some extent on the basis of your genes. Preventive DNA analysis can therefore be an important tool in optimising your medication.

Flecainide and the enzyme CYP2D6

Flecainide is processed to a large extent by the enzyme CYP2D6. The activity of this enzyme can vary considerably depending on your genetic predisposition, which means the efficacy of flecainide can also differ from person to person.

Information about your genetic predisposition may therefore provide grounds for extra vigilance in relation to a treatment with flecainide.

Read more about The enzyme CYP2D6 »
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